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differential liver management algorithm lactate acidosis aclf aih amiodarone autoimmune cardiology causes chronic cirrhosis classification dehydrogenase dili druginduced elevated elevation
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Brain Failure Lung ... Drug-Induced Liver Injury ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... CA, small cell lung ... #diagnosis #algorithm ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... dechallenge • Acute ... #Diagnosis #Algorithm ... #hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... Legionnaires disease • Pulmonary ... Pneumonia • Other lung ... : • Early acute ... hepatitis • Acute
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... subclinical disease to acute ... pattern of liver injury ... regarding need for treatment ... #Management #Hepatology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
injury • Indirect ... starting amiodarone treatment ... pleural effusions • Acute ... toxicity (e.g., acute ... macrophages Treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
liver or renal injury ... before beginning treatment ... cardiac output - Acute ... pulmonary edema ... peritonitis - Acute
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
, verrucous) - Lung ... Culture Positive: • Acute ... Cerebral > Splenic, Pulmonary ... Septic emboli cause injury ... hematuria, + RF Treatment
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