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Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
lung diseases ... I-JIP: usual interstitial ... AIP: acute interstitial ... PSS: Sjogren syndrome ... #Comparison #Table
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
Interstitial Lung ... lung disease (RB-ILD ... Churg Strauss syndrome ... #differential # ... pulmonary #causes
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Differential Diagnosis ... Pneumonia • (UIP ... Lymphangioleiomyomatosis (LAM), • Pulmonary ... leaking out of pulmonary ... #ILD #Causes #Differential
The idiopathic interstitial pneumonias (IIPs) comprise a heterogenous group of disorders. 
They represent fundamental responses of
listed in the table ... findings of NSIP, UIP ... Diagnosis #Radiology #Pulmonary ... #CTChest #Idiopathic ... IdiopathicInterstitialPneumonia #ILD
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
Upper lung zone ... bronchiolitis (RB-ILD ... is seen in: - UIP ... HRCT #ChestCT #Differential ... #Table #Distribution
Ground-glass opacity
Ground-glass opacity (GGO) represents:
- Filling of the alveolar spaces with pus, edema, hemorrhage, inflammation or
lung disease (i.e ... predominance: UIP ... Diagnosis #Radiology #Pulmonary ... #CTChest #GGO # ... #GroundGlass #Differential
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
Differential diagnosis ... lung disease comes ... low attenuation (table ... in many cases UIP ... Diagnosis #Radiology #Pulmonary
Figure 3 HRCT-LUS correlation in normal lung, pulmonary congestion, rheumatoid lung disease, idiopathic pulmonary fibrosis.
Notes: (A)
due to alveolar syndrome ... fibrotic alveolar syndrome ... artifact); (G) UIP ... #Correlation #Table ... #ILD #Findings
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm
Pericardial
 • Effusion
 • Cardiac Tamponade*
 • Constriction
Myocardial
 •
Chronic Dyspnea - Differential ... Artery Disease • Stable ... Acute Coronary Syndrome ... Interstitium ... • ILD • CHF
Causes of Hypoxemia- Differential Diagnosis Algorithm
Ventilation/perfusion Mismatch
 • Airway Disease (Asthma, COPD)
 • Vascular (PE*)
 •
of Hypoxemia- Differential ... Limitation • Interstitial ... lung disease ... Hypoventilation Syndrome ... Abnormalities • Chest