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Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
lung diseases ... I-JIP: usual interstitial ... AIP: acute interstitial ... PSS: Sjogren syndrome ... #Rheumatology #
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
Interstitial Lung ... lung disease (RB-ILD ... Churg Strauss syndrome ... #differential # ... pulmonary #causes
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm
Pericardial
 • Effusion
 • Cardiac Tamponade*
 • Constriction
Myocardial
 •
Chronic Dyspnea - Differential ... Acute Coronary Syndrome ... Interstitium ... • ILD • CHF ... Chronic #Dyspnea #SOB
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Dyspnea - Differential ... • Parenchyma: ILD ... Hepatopulmonary syndrome ... Pain #dyspnea #sob ... #differential #
Ground-glass opacity
Ground-glass opacity (GGO) represents:
- Filling of the alveolar spaces with pus, edema, hemorrhage, inflammation or
So ground-glass ... lung disease (i.e ... Diagnosis #Radiology #Pulmonary ... #CTChest #GGO # ... #GroundGlass #Differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial ... lung disease - ... • Shrinking lung ... #joint #pain #differential ... #diagnosis #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... MALT Lymphoma • Lung ... #Rheumatology #
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone Induced Lung ... Direct cytotoxic lung ... respiratory distress syndrome ... (e.g., chronic interstitial ... Exclusion of other ILDs
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Anti-MDA5 (RP-ILD ... ), dermato-rheumatologic ... weakness + atrophy- Hip ... #differential #
Authors: Mark M. Ramzy, DO, EMT-P (@MarkRamzyDO, EM Resident Physician, Drexel University, Department of Emergency Medicine)
This post will focus ... Because this breaks up ... does a better job ... #Radiology #CTChest ... #Lung #Pulmonary