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management fungal infectiousdiseases amiodarone antibiotics blastomyces blastomycosis cdi cdiff clostridioides clostridium common coverage curb65 cvid difficile gastroenterology hematology hypogammaglobulinemia idsa
Community Acquired Pneumonia - Severity and Prognosis Criteria for Severe CAP - Severe CAP present in 1
Community Acquired ... in 1 major criterion ... criteria: Septic shock ... #Community #Acquired ... #severe #psi #diagnosis
Community Acquired Pneumonia - Presenting Features • History in favor of CAP: Dyspnea, Cough, particularly if
Community Acquired ... Pneumonia - Presenting ... in 1 major criterion ... #Community #Acquired ... #Pneumonia #diagnosis
Antibiotics for severe community-onset pneumonia Atypical coverage always - Usually azithromycin 500 mg daily - Doxycycline
pneumonia Atypical ... piperacillin-tazobactam Septic Shock ... Structural lung ... #Acquired #Pneumonia ... #CAP #Antibiotics
Community Acquired Pneumonia (CAP) - Diagnosis and Management Pneumonia Signs/Symptoms: • Confusion/disorientation (LR + 1.9) • Cough
Community Acquired ... Pneumonia (CAP) ... Egophony (May appear 1- ... #CAP #Diagnosis ... #Pulmonary #Community
Blastomycosis (Blastomyces): Gilchrist’s disease, Chicago disease - Summary Sheet • Morphology • Geography, Reservoir and Mode
blastomycosis – resembles community-acquired ... pneumonia with ... presentation of TB, lung ... Amphotericin B for 1- ... #Blastomyces #diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Epidemiology: • #1 ... post-ABx, but can ... be community-acquired ... 10 mg/kg IV x 1
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... and 1:50,000 patients ... -> 40 years • Can ... frequent and severe community-acquired ... infections: Pneumonia
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Amiodarone Induced Lung ... Direct cytotoxic lung ... starting amiodarone treatment ... including: 1. ... macrophages Treatment
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
clinical forms: 1) ... disseminated) can ... change in the lungs ... fever • Septic shock ... nails, bronchi, lungs
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... Antinuclear antibodies ≥ 1: ... , INC risk PE, Pulmonary ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment
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