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Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm

By Matthew Ho, MD PhD @MatthewHoMD

#Diffuse
lymphoma (DLBCL ... Management and Treatment ... #lymphoma #DLBCL ... #Algorithm #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
typically of B-cell ... Pel-Ebstein fever - Alcohol-induced ... • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
the non-Hodgkin lymphoma ... microglobulin Treatment ... lymphoma • Hairy ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma ... Pain in LN on alcohol ... Treatment • Early ... classification #hematology ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Purtilo (XLP) Acquired ... lymphoma, B-cell ... lymphoma (DLBCL ... Unknown cause Treatment ... #summary #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Transformation to large cell ... lymphoma (Richter ... transformation) Treatment ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Hepatic artery: Shock ... VZV • Trauma: Shock ... lung CA, lymphoma ... ALT Ratios: • Alcoholic ... diagnosis #algorithm #hepatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
arsenic compounds, alcohol ... factor (GCSF) treatments ... marrow studies Treatment ... Syndromes #diagnosis #hematology ... #oncology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
Bone marrow Treatment ... chemotherapy as required ... • Non-Hodgkin Lymphoma ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology