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management rheumatology 1 activation antibiotic arteritis cdi cell clinical clostridioides clostridium cutaneous dermatology differential difficile failure gastroenterology gca giantcell hemophagocytic
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Difficile Infection ... Toxic Megacolon, Shock ... can be community-acquired ... Ileus, Megacolon, Shock ... ciab549 #CDI #Cdiff
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
- Differential Diagnosis ... Framework Diagnosis ... Immunocompromise Treatment ... • Secondary to Treatment ... (C diff) • Hospital-Acquired
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Purtilo (XLP) Acquired ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
the secondary or acquired ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis vs infection ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology ... w/in 24 hours) required
Cutaneous larva migrans skin Rash 25 F recent Caribbean vacation, walked barefoot on sand and now with
with creepy rash. diagnosis ... self-limited Diagnosis ... No treatment is ... required unless ... Indiana University Infectious
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... • CBC + diff • ... Bone marrow Treatment ... chemotherapy as required ... #Workup #Hematology
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