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management 1 antibiotic cdi cdiff clostridioides clostridium differential difficile emergencies failure gastroenterology hemophagocytic hlh infection infectiousdiseases lymphohistiocytosis orthopedics rheumatology summary
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Bug: Atypical bacteria ... Immunocompromise Treatment ... • Secondary to Treatment ... diff) • Hospital-Acquired ... Difficile, COVID
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Infection (CDI) ... Toxic Megacolon, Shock ... can be community-acquired ... Tx Management (IDSA ... Ileus, Megacolon, Shock
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Purtilo (XLP) Acquired ... CMV, HHV8,...), Bacteria ... diseases: SLE+++, Adult-onset ... Unknown cause Treatment ... #management #treatment
Orthopedic Emergencies Compartment Syndrome • An increase in compartment pressure to the point where tissue perfusion is
fractures in young adults ... progressive inflammatory infection ... • Diagnosis: ... #Emergencies #diagnosis ... #management #treatment
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