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rheumatology treatment differential disease vasculitis arteritis classification coronavirus covid19 encephalopathy gca giantcell hemophagocytic hlh inflammatory leukostasis lymphohistiocytosis lysis multisystem neurology
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS) Clinical features all: fever > 101.3 F most: oxygen
Pediatric Inflammatory ... Multisystem Syndrome ... mucus membrane changes ... #coronavirus #diagnosis ... #Signs #Symptoms
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... azathioprine #Behcet ... #Syndrome #diagnosis ... #management #signs ... #symptoms #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
tinnitus, visual changes ... , stroke symptoms ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... -60y (hormonal changes ... at the time of diagnosis ... #Management #Signs
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... and Management ... Romana's sign ... /symptoms, positive ... #Management #Treatment
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... symptoms can mimic ... #management #treatment ... #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Seizures • Vision changes ... Infection/Sepsis/Shock ... Neurological symptoms ... territories signal changes ... #diagnosis #management
Pheochromocytoma - Diagnosis and Management Summary 10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
bilateral, malignant, pediatric ... life • M=F Symptoms ... and Signs: 50% ... mental status changes ... and signs: •
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... headaches, vision changes ... GCA #Temporal #Signs ... #Symptoms #Diagnosis ... #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... • Progressive symptoms ... and gray matter changes ... vasculitis • Behcet ... #Rheumatology
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