8 results
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Liver ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm ... #causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Differential Diagnosis Algorithm ... Primary Causes ... • Cholestatic liver ... renal failure/uremia ... #causes
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
, - regional ischemia ... of lactate as a clinical ... presentations and disease ... of Circulatory System ... 30mmHg) - Severe anemia
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
sepsis: chronic liver ... disease, iron overload ... hemochromatosis, hemolytic anemia ... immunosuppressive meds ... #legs #clinical
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
• Cholestatic liver ... renal failure/uremia ... Pruritus #secondary #systemic ... #generalized #dermatology ... #causes
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Liver diseases ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... vasculitis: 10%-16% Liver ... renal tubular acidosis ... Nephrogenic DI Hematologic
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
the Fingers Clinically ... Systemic causes ... include diabetes, anemia ... hyperthyroidism, peripheral ischemia ... Seen in liver disease