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diagnosis dermatology differential management photo rheumatology secondary classification generalized pruritus rash abnormal acidosis atlas beaus canimorsus capnocytophaga cellulitis common cryofibrinogenemia
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Primary Causes ... • Cholestatic liver ... renal failure/uremia ... #causes
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Liver ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm ... #causes
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
toxic aetiology: Skin ... for alternative causes ... disease, Hepatic ... ischaemia, Autoantibody ... #hepatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... renal failure/uremia ... Pruritus #secondary #systemic ... #generalized #dermatology ... #causes
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
Vibrio Vulnificus skin ... sepsis: chronic liver ... hemochromatosis, hemolytic anemia ... immunosuppressive meds ... #legs #clinical
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
processes: • Systemic ... limb and bowel ischemia ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
, - regional ischemia ... of lactate as a clinical ... presentations and disease ... of Circulatory System ... 30mmHg) - Severe anemia
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Liver diseases ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Syndrome: • Clinical ... • Autoimmune diseases ... - (Ischemia,
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic
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