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diagnosis differential hepatology injury lfts rheumatology transaminitis abnormal autoimmune biliary cholangitis cirrhosis dili druginduced gap globulin liverenzymes liverfunctiontests myopathy myositis
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Elevated Transaminases ... Trauma: Shock liver ... See Updated Schema ... Differential #Diagnosis #causes ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... Drugs/Toxins • Ischemia ... • Alcoholic hepatitis ... #Causes
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... disease, Hepatic ischaemia ... • Autoimmune hepatitis ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... Drugs, Viral, Ischemia ... kwburak #LFTs #Elevated ... #diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... specificity to elevated ... differential #diagnosis #algorithm ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... or higher • Liver ... Diagnosis: • Viral hepatitis ... cholangitis #diagnosis #workup ... #hepatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis: • Purpura, ischemic ... and mesenteric ischemia ... • Elevated ESR ... tract, and often causes ... - interstitial keratitis
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... frequently affected systems ... heme (bleeding), CV ... Better call hematology ... #workup #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Elevated Globulin ... Albumin > 4) Work-up ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... differential #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
kinase levels are elevated ... • Conduction system ... statins - probably caused ... PBC, autoimmune hepatitis ... Myositis #Myopathy #rheumatology
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