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diagnosis differential liver injury lfts causes transaminitis abnormal aclf acute chronic druginduced elevated failure gastroenterology hepatocellular hepatomegaly liverenzymes liverfunctiontests management
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Drugs/Toxins • Ischemia ... • Autoimmune ... • Drugs • AIH ... hepatitis • Drugs ... Infiltrative • Cirrhosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
HEV, EBV, CMV), Alcohol-related ... disease, Hepatic ischaemia ... steatosis • Autoimmune ... hepatitis #DILI ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Inflammatory • Alcoholic ... Hepatitis • Autoimmune ... Primary Biliary Cirrhosis ... #Causes #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure Infections Alcohol-Associated ... Hepatitis (AAH) ... Liver Injury (DILI ... ) Viral Hepatitis ... #Hepatology #gastroenterology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Differential Diagnosis Algorithm ... Drugs, Viral, Ischemia ... - NAFLD, Alcohol ... Congenital, Others, Cirrhosis ... #diagnosis #hepatology
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
Clinical Diagnosis of Autoimmune ... Hepatitis - Onset ... factors - Possible ischemic ... SMA >1:80 #Autoimmune ... #Hepatology #AIH
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
: Autoimmune hepatitis ... • Iatrogenic: DILI ... ALT Ratios: • Alcoholic ... : < 1 • Cirrhosis ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... Other: NAFLD, Autoimmune ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis
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