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differential hyperkalemia management nephrology potassium behcet cardiology classification dili disease druginduced elevation endocarditis hematology infectiousdiseases lactate lactic leukostasis liver lysis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... disease, Hepatic ischaemia ... #Diagnosis #Algorithm ... #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
liver or renal injury ... perfusion - shock->treatments ... before beginning treatment ... - Compartment syndrome ... gluconeogenesis Liver Injury
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... WBC count cause ... AKI, acute limb ischemia ... Spontaneous if high ... #TLS #diagnosis
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• Trauma/Crush injury ... - Tumor lysis syndrome ... burns, trauma - Ischemic ... - Metabolic acidosis ... #causes #potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• Trauma/Crush injury ... - Tumor lysis syndrome ... burns, trauma - Ischemic ... - Metabolic acidosis ... #causes #potassium
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
to local skin injury ... sinus thrombosis, VTE ... retinal tears, Ischemia ... Arthritis, AS Treatment ... exacerbations: high-dose
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Cholesterol emboli syndrome ... Septic emboli cause ... injury by: • Early ... embolic/ischemic ... hematuria, + RF Treatment
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