7 results
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... organs leading to ischemia ... , necrosis and pain ... #Complications ... #Hematology #Sequelae
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... • Mechanism: ischemic ... other orthopedic complications ... differential #diagnosis #causes ... #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... vomiting, abdominal pain ... Monitor and Treat Complications ... Liver #Pregnancy #hepatology ... #obstetrics #obgyn
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... neurology, back pain ... Haematology - ... #Limping #NWB #Algorithm ... Pathway #Child #Peds
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
CNS and hematologic ... leading to organ ischemia ... jaundice and RUQ pain ... #Immunization #peds ... #pediatrics #pathophysiology
Portal Vein Thrombosis (PVT) Treatment Algorithm
 - If concern for ischemic: anti-coag+multidisciplinary care
 - W/o cirrhosis+recent
PVT) Treatment Algorithm ... If concern for ischemic ... - Cirrhosis: case-by-cased ... partially occlusive main ... #hepatology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
, symptoms and complications ... atypical chest pain ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology