4 results
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
organs leading to ischemia ... , necrosis and pain ... #SickleCell #Disease ... #Complications ... #Hematology #Sequelae
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... • Mechanism: ischemic ... other orthopedic complications ... #SickleCell #Disease ... #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... vomiting, abdominal pain ... Monitor and Treat Complications ... #obstetrics #obgyn
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
CNS and hematologic ... leading to organ ischemia ... jaundice and RUQ pain ... #Immunization #peds ... #pediatrics #pathophysiology