8 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the ... of Sickle Cell Crises ... Diagnosis #Management #Hematology ... #SickleCell #Complications ... Manifestations #Workup #Algorithm
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... organs leading to ischemia ... #SickleCell #Disease ... #Complications ... #Hematology #Sequelae
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... • Mechanism: ischemic ... other orthopedic complications ... #Joint #Pain #SickleCell ... #hematology
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
re-vascularize the ischemic ... causes upregulation ... Retinopathy #Diabetes #ophthalmology ... #diagnosis #complications ... #pathophysiology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
fluffy white ischemic ... Elschnig's Spots • Ischemia ... #Retinopathy #pathophysiology ... #ophthalmology ... signs #symptoms #complications
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Anterior ischemic ... Is visual loss caused ... the optic nerve caused ... #Ophthalmology ... #Diagnosis #Algorithm
Treatment of giant cell arteritis (GCA)

1st Line Strategy - GC 0.7 mg/kg/day, except for:
 • Aortitis
mg/kg/day • Ischemic ... complications - ... MTX or TCZ in case ... #Indications #rheumatology ... #2ndline
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
anti-coagulation • Hematologic ... retinal edema caused ... by ischemia results ... Occlusion #CRAO #pathophysiology ... #ophthalmology