45 results
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
- Pathophysiology ... complications ... organs leading to ischemia ... #Complications ... #Hematology #Sequelae
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
re-vascularize the ischemic ... causes upregulation ... Retinopathy #Diabetes #ophthalmology ... #diagnosis #complications ... #pathophysiology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Anterior ischemic ... Is visual loss caused ... the optic nerve caused ... #Ophthalmology ... #Diagnosis #Algorithm
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Causes of Dizziness ... Differential Diagnosis Algorithm ... • Meniere's Disease ... • Transient Ischemic ... #Causes
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
fluffy white ischemic ... #Retinopathy #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms ... #complications
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... Intestine - Other causes ... Most common symptoms ... - Bone symptoms ... #hepatology
Diplopia - Double Vision - Differential Diagnosis Algorithm
Clinical Pearls:
 • Diplopia is almost always binocular.
 •
Differential Diagnosis Algorithm ... • Neurologic symptoms ... a mass as the cause ... Differential #Diagnosis #Algorithm ... #Causes #Ophthalmology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... • Mechanism: ischemic ... other orthopedic complications ... #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Differential Diagnosis Algorithm ... Drugs/Toxins • Ischemia ... • Cholestatic disease ... Others #LFTs #Hepatology ... #Causes
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
anti-coagulation • Hematologic ... retinal edema caused ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms