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diagnosis management differential amyotrophic hematology lateral leukostasis lysis myasthenia nephrology rhabdomyolysis rheumatology sclerosis treatment tumor vasculitis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... AKI, acute limb ischemia ... WBC >100k, + lab signs ... leukapheresis - TLS ... #TLS #diagnosis
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Generalized fatigue - ALS ... test - Cogan sign ... - Peek sign ... Myasthenia Crises ... diagnosis #management #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... ) Summary ALS: combination ... lateral sclerosis Pathophysiology ... - Causes progressive ... Lateral #Sclerosis #neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... HIV, Influenza, TSS ... perfusion → renal ischemia ... kidney tubular cells ... #treatment #nephrology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... Multinucleated giant cells ... affects the skin, neurologic ... cognitive impairment, neurologic ... tract, and often causes
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