23 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
AKI, acute limb ischemia ... WBC >100k, + lab signs ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... life-threatening Differential ... test - Cogan sign ... - Peek sign ... immunologic assay - MuSK
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... Radiology Imaging ... mass and NO prior signs ... Differential diagnosis ... #msk #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behcet disease) Differential ... retinal tears, Ischemia ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
STEMI Equivalents on ECG
 • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
point • De Winter syndrome ... V2 • Wellens sign ... pain • Wellens sign ... deviation) • Acute ischemia ... EKG #diagnosis #differential
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
workup 1) Clinical ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... Unique or multiple ischemic ... MNCD #Dementia #Differential
Freiberg Infraction - MSK Radiology
Imaging Findings:
 • Sclerosis of the 2nd MT head with flattening of
Freiberg Infraction - MSK ... for secondary signs ... Differential diagnosis ... #mri #clinical ... #msk
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... hyperthermia crisis (late sign ... • Serotonin syndrome ... #Hyperthermia #Differential
Medial Meniscus Bucket Handle Tear - MSK Radiology
Imaging Findings:
 • Truncation of the medial meniscus on
Handle Tear - MSK ... The "double PCL sign ... Differential diagnosis ... Tear #knee #mri #clinical ... #msk