14 results
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
retinal tears, Ischemia ... , AS Treatment: ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... Must rule out other ... #AOSD #rheumatology ... #diagnosis #management ... #treatment
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... present, symptoms, signs ... von Willebrand disease ... PV #Diagnosis #Management ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Purpura, ischemic ... Kidneys: glomerular ischemia ... purpura: strong sign ... Vessels: Supply gut ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura, ischemic ... purpura: Strong sign ... and mesenteric ischemia ... purpura, joint & gut ... Differential #Diagnosis #Rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... frequent attacks • Arthritis ... double contour sign ... +Radiographic signs ... #treatment #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
AKI, acute limb ischemia ... WBC >100k, + lab signs ... organ damage • Treatment ... TLS #diagnosis #management ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
juvenile idiopathic arthritis ... juvenile idiopathic arthritis ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... Diagnosis: HLH signs ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology