10 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... visual changes, stroke ... AKI, acute limb ischemia ... organ damage • Treatment ... diagnosis #management #hematology
Treatment of giant cell arteritis (GCA)

1st Line Strategy - GC 0.7 mg/kg/day, except for:
 • Aortitis
Treatment of giant ... mg/kg/day • Ischemic ... scalp necrosis, stroke ... MTX or TCZ in case ... #Indications #rheumatology
Abdominal Distention - Differential Diagnostic Algorithm
Ascites
Bowel Dilatation
Other Causes
Mechanical Obstruction
 • Adhesions 60%
 • Volvulus 3%
 •
Abdominal Distention ... Dilatation Other Causes ... Infectious • Ischemic ... Spinal Injury, Stroke ... ) #Abdominal
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Heat injury, Heat stroke ... Tachycardia - N/V - Abdominal ... perfusion → renal ischemia ... Diagnosis #Management #causes
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura, ischemic ... and mesenteric ischemia ... Non-glomerular ischemia ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Related conditions: Stroke ... limb and bowel ischemia ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Purpura, ischemic ... tract, and often causes ... Kidneys: glomerular ischemia ... Palpable purpura: strong ... differential #diagnosis #rheumatology
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
cannot, coronary ischemia ... treat the primary cause ... may not be the case ... #diagnosis #algorithm ... criticalcare #foamed #treatment
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... MI, stroke, DVT/ ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
history of: a) Ischemic ... event, follow ACC algorithm ... one post op Cardiology ... • <6mo since stroke ... undergoing AAA or upper abdominal