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diagnosis hematology management differential endocarditis 2ndline arteritis bone checklist cryofibrinogenemia disease essential et evaluation gca giantcell indications infectiousdiseases joint leukostasis
How do you work up an ischemic CVA? A) Initial Evaluation • ABCs • IV access, monitor
How do you work ... up an ischemic CVA ... ) B) Evaluate ischemic ... udaygulati #ischemic ... #CVA #stroke #workup
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... • Mechanism: ischemic ... other orthopedic complications ... differential #diagnosis #causes ... #hematology
Treatment of giant cell arteritis (GCA) 1st Line Strategy - GC 0.7 mg/kg/day, except for: • Aortitis
mg/kg/day • Ischemic ... complications - ... scalp necrosis, stroke ... MTX or TCZ in case ... #Indications #rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... tissue damage from ischemia ... hematuria (without casts ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... visual changes, stroke ... AKI, acute limb ischemia ... diagnosis #management #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Related conditions: Stroke ... limb and bowel ischemia ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Septic Emboli Cause ... Early embolic/ischemic ... Treat underlying cause ... destructive lesion • Complications ... diagnosis #management #cardiology
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
adverse events or complications ... history of: a) Ischemic ... b) CHF c) CVA ... one post op Cardiology ... • <6mo since stroke
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Septic emboli cause ... Early embolic/ischemic ... Treat underlying cause ... destructive lesion • Complications ... Differential #Diagnosis #cardiology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... , symptoms and complications ... patients with no CV ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
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