10 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... • Mechanism: ischemic ... #SickleCell #Disease ... differential #diagnosis #causes ... #hematology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
Differentiate Acute ... from Myocardial Ischemia ... from myocardial ischemia ... associated with rheumatologic ... life-threatening causes
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
organs leading to ischemia ... , necrosis and pain ... #SickleCell #Disease ... Complications #Hematology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Other • ATN: Ischemia ... Pigment, Protein) • AIN ... SCVMCMed #AKI #Acute ... #causes #algorithm
Extrapulmonary manifestations of COVID-19
 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke
 • Renal:
of COVID-19 • Neurologic ... Stroke • Renal: Acute ... vomiting, Abdominal pain ... shock, Myocardial ischemia ... , Acute cor pulmonale
Portal Vein Thrombosis (PVT) Treatment Algorithm
 - If concern for ischemic: anti-coag+multidisciplinary care
 - W/o cirrhosis+recent
If concern for ischemic ... anti-thrombotic tx - Cirrhosis ... : case-by-cased ... partially occlusive main ... management #Algorithm #hepatology
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Crises can be precipitated ... associated with severe pain ... capillaries leading to ischaemia ... 2) Aplasia - Acute ... deficiency #SickleCell
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - ACS, AKI, acute ... limb ischemia, ... diagnosis #management #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura, ischemic ... and mesenteric ischemia ... Non-glomerular ischemia ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... , with ensuing ischemia ... muscle aches, joint pain ... , chest pain • ... , neutropenia, cirrhosis