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hepatology diagnosis liver differential aflp causes hepatitis obstetrics unconjugated algorithm alkphos astalt biliary biochemistry chemistry cholangitis cirrhosis classification comparison disease
Bilirubin Metabolism - Pathophysiology • Conjugated Bilirubin • Unconjugated Bilirubin By Dr. Khushboo Gala @LouLectures #Bilirubin #Metabolism #Pathophysiology
Bilirubin Metabolism ... - Pathophysiology ... • Conjugated ... Bilirubin • Unconjugated ... #Metabolism #Pathophysiology
Biochemistry and Metabolism of Bilirubin Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
Biochemistry and Metabolism ... Conjugation → Conjugated ... , and conjugated ... #Biochemistry #Metabolism ... #pathophysiology
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... conjugates (eg, ... cholestasis of pregnancy ... postoperative jaundice ... neoplasms #Jaundice
Jaundice - Pathophysiology and Causes - Amy Chung, MD, MSc @AmyChung #Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... Amy Chung, MD, MSc ... @AmyChung #Jaundice ... #Pathophysiology ... #Differential #Unconjugated
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... acid metabolism ... acid metabolism ... (DIC, ascites, jaundice
Bilirubin metabolism and pathophysiology of jaundice #Bilirubin #metabolism #pathophysiology #jaundice #hepatology
Bilirubin metabolism ... and pathophysiology ... of jaundice # ... Bilirubin #metabolism ... #pathophysiology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Metabolism AST ... metabolism: • ... MRP2 transports conjugated ... Tests #Laboratory #Metabolism ... #Hepatology #Pathophysiology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Pruritus, Mild jaundice ... fold elevation, Bilirubin ... fold elevation, Bilirubin ... hemorrhage Acute Fatty ... Hepatic imaging: Fatty
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... hyperpigmentation • Jaundice ... slightly elevated • Bilirubin ... cholestasis of pregnancy
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Shock liver • Metabolic ... melanoma, myeloma • Pregnancy ... week • Direct bilirubin ... injury: ~ 1 Unconjugated ... Elevation: • Bilirubin
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