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diagnosis hematology antigen biliary carcinoembryonic cea cholangitis cirrhosis comparison gap globulin hellp icp liver mds myelodysplasia myelodysplastic obstetrics pbc pregnancy
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... Pruritus, Mild jaundice ... #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
hyperpigmentation • Jaundice ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... cholangitis #diagnosis #workup ... #hepatology
Carcinoembryonic antigen (CEA) • CEA is a highly glycosylated cell surface glycoprotein involved in intercellular adhesion
Rectal polyps, Hepatitis ... cirrhosis, Obstructive jaundice ... Smokers, Renal disease ... CEA #diagnosis #laboratory ... #oncology #differential
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... • Plasma cell leukemia ... • Heavy chain disease ... : Lymphoma, Leukemia ... Gap #ProteinGap #differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... Workup: • Complete ... blood count with differential ... #oncology
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