15 results
An Approach to Jaundice Workup Algorithm by CBC and LFT Pattern

- Dr. Eric Strong @DrEricStrong

#Jaundice #Workup
An Approach to Jaundice ... Workup Algorithm ... by CBC and LFT ... #Patterns #LFTs ... #Diagnosis #Hepatology
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
Important findings: jaundice ... Focus on prior Liver ... - Vitals - LFTs ... disease work up ... Calling #Referral #Hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Tests (LFTs) - ... Hepatopathy • Acute ... Function #Tests #LFTs ... Differential #Diagnosis #hepatology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Cell Disease Acute ... onset RUQ pain, jaundice ... liver failure ... Liver transplant ... Hepatobiliary #hepatology
Shotgun Laboratory Testing for Severe Acute Livery Injury

https://www.journalofhospitalmedicine.com/jhospmed/article/143598/hospital-medicine/ammonia-levels-and-hepatic-encephalopathy-patients-known

#TWDFNR #Testing #Laboratory #LiverInjury #Diagnosis #Workup #Hepatology #EBM #ChoosingWisely
Testing for Severe Acute ... Livery Injury ... LiverInjury #Diagnosis #Workup ... #Hepatology #EBM
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... > 20x normal - Acute ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... Hepatocellular - Check Acute ... Mixed - Check Acute ... #differential #Hepatology ... transaminitis #LFTs
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... headache, malaise) → Acute ... (DIC, ascites, jaundice ... #Pregnancy #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Pruritus, Mild jaundice ... and hemorrhage Acute ... Fatty Liver of ... Disease #Pregnancy #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... gastric bypass), LFT ... (liver disease) ... #hematology