10 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... Malaise, bleeding, infections ... pain, bleeding, infections ... • Age: 60-80 Clonal ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... cytometry → >500/uL clonal ... immunophenotype Clinical ... Complications: 1) Infection ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... with no early symptoms ... weeks without infection ... diagnosis #workup #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... Autoimmune diseases • Clinical ... involved) • No leukemic ... Etiology: - Infections ... NonHodgkins #comparison #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... Idiopathic • Infections ... virus (EBV) • Leukemia ... • Improve the symptoms ... Aplastic #Anemia #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... ingestion • B symptoms ... subtypes: - Nodular sclerosis ... #oncology #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Marrow Failure • Chronic ... Myelogenous Leukemia ... • Hairy Cell Leukemia ... #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... fibromyalgia) • Infections ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Rheumatologic ... • Sclerosing mediastinitis ... 85% • < 50% in chronic ... has five major clinical ... fungal stain of clinical
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
cytopenias, and clonal ... with a risk of clonal ... acute myeloid leukemia ... may result in an infection ... importance of clinical