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diagnosis hematology management cll lymphocytic neurology rheumatology algorithm anemia aplastic behcet cancer cord differential disease erythematosus hemeonc lesions lupus mds
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... develop leukostasis syndrome ... • Tumor lysis syndrome ... • Age: 60-80 Clonal ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... cytometry → >500/uL clonal ... immunophenotype Clinical ... uw_IMresidency #CLL #Chronic ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... with no early symptoms ... #CLL #Chronic ... diagnosis #workup #oncology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Hyperreflexia, Clonus ... Signs and symptoms ... patients with clinically ... stimulation Clinical
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
injury - Multiple sclerosis ... Lower motor neuron symptoms ... Upper motor neuron symptoms ... degeneration - Multiple sclerosis ... are spared Conus
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... virus (EBV) • Leukemia ... • Improve the symptoms ... Aplastic #Anemia #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... meningitis), MCC CNS symptoms ... (Clinical Dx). ... tears, Ischemia, Leukemia ... Recurrent and chronic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Marrow Failure • Chronic ... Myelogenous Leukemia ... • Hairy Cell Leukemia ... diagnosis #hematology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Clinical Features ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... cytopenias, and clonal ... with a risk of clonal ... acute myeloid leukemia ... importance of clinical
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