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hematology leukemia management chronic cll lymphocytic aplastic cancer checkpointinhibitor classification gammopathy hemeonc hodgkins lymphoma mds mgus monoclonal myelodysplasia myelodysplastic sideeffects
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
mutations) • Immune ... HCV - HIV • Immune ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... cytometry → >500/uL clonal ... of anemia or thrombocytopenia ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology
Immune Checkpoint Inhibitor Toxicity Main Toxicities: Colitis, Pneumonitis, Skin adverse events, Endocrine dysfunction, Hepatitis, Myocarditis,
Immune Checkpoint ... Incidence, Symptoms ... SideEffects #Table #Diagnosis ... #Pharmacology # ... Oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
No evidence of anemia ... constitutional symptoms ... insufficiency, Anemia ... Significance #hematology #diagnosis ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune ... with no early symptoms ... phenomenon CLL Diagnosis ... • Neutropenia, anemia ... #workup #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... - infiltrates (anemia ... • Age: 60-80 Clonal ... Leukemia #Hematology #Oncology ... #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Erythema nodosum • Immune ... hemolytic anemia ... ingestion • B symptoms ... classification #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... • Aplastic Anemia ... Significance (IDUS) • Immune ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
current treatment algorithm ... cytopenias, and clonal ... with a risk of clonal ... median age at diagnosis ... disease tolerate anemia
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