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hematology chronic cll lymphocytic management anemia aplastic cancer checkpointinhibitor hemeonc mds myelodysplasia myelodysplastic sideeffects syndromes table toxicities toxicity workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... • Age: 60-80 Clonal ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Most common leukemia ... minimal tumor burden Diagnosis ... cytometry → >500/uL clonal ... #oncology #hematology ... #hemeonc #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune ... with no early symptoms ... phenomenon CLL Diagnosis ... #diagnosis #workup ... #oncology #hematology
Immune Checkpoint Inhibitor Toxicity Main Toxicities: Colitis, Pneumonitis, Skin adverse events, Endocrine dysfunction, Hepatitis, Myocarditis,
Immune Checkpoint ... Incidence, Symptoms ... SideEffects #Table #Diagnosis ... #Pharmacology # ... Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
mutations) • Immune ... virus (EBV) • Leukemia ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... • Hairy Cell Leukemia ... Significance (IDUS) • Immune ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
current treatment algorithm ... cytopenias, and clonal ... with a risk of clonal ... acute myeloid leukemia ... median age at diagnosis
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