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diagnosis clinical physicalexam hematology differential algorithm management ophthalmology workup microscopy causes anemia smear pathophysiology slitlamp hepatology bloodsmear neurology pathology syndrome
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Pathologic Red Blood ... Cell (RBC) Morphologies ... cell, Other RBC ... bodies, Howell-Jolly ... bodies #RBC
Post-splenectomy blood smear demonstrating Howell-Jolly bodies and target cells. #Clinical #Pathology #BloodSmear #HowellJollyBodies #TargetCells #Splenectomy #Asplenic
Post-splenectomy blood ... demonstrating Howell-Jolly
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Common RBC Inclusions ... Associations • Howell Jolly ... Sickle cell, MDS #RBC
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... / Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Disorder • RBC
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
Blood Product Components ... Life Whole blood ... directed donations) - RBC ... Hct 35%. 450mL blood ... plasma, a few RBC
ABO Blood Types and Transfusion Compatibility Table A Blood Type: • RBC Antigens: A • Antibodies: Anti-B
ABO Blood Types ... Type: • RBC Antigens ... Type: • RBC Antigens ... Type: • RBC Antigens ... Type: • RBC Antigens
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... cells (RBCs or ... serum due to the RBCs ... Clinical #Path #Blood ... Smear #Microscopy #RBC
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... cells (RBCs or ... serum due to the RBCs ... Clinical #Path #Blood ... Smear #Microscopy #RBC
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
(MCV): Average RBC ... among size of RBCs ... wide range of RBC ... in peripheral blood ... High in acute blood
Plasmodium falciparum life cycle 1: Mosquito bite, transmission of sporozoite 2: Liver, Asexual replication. 1 sporozoite → 10-30,000
merozoites 3: Blood ... Merozoites infect RBC ... RBC ruptures releasing ... Merozoites infect other RBCs
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