12 results
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Algorithm • 40- ... fatigue despite clinical ... Receptor (sTfR) to differentiate ... /other causes • ... #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammation of the bones ... Rheumatic pain Clinical ... Diagnosis: • A clinical ... Rule out other causes ... Rheumatology #diagnosis #management
Notice that there are multiple densities in both lungs.
The larger ones are ill-defined and maybe there
The larger ones ... are ill-defined ... masses. ... dealing with the differential ... #Clinical #Radiology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... ↓Antithrombin Ill ... infiltration) Differential ... #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... , Biological + Bone ... /ml, ↑ LDH • Bone ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Myasthenic Crisis Checklist - Myasthenia Gravis

Evaluation 
 - Chest X-ray and lung ultrasound (exclude other lung
Phos), CBC with differential ... Intubation only if clinically ... (vital signs, clinical ... to avoid (main ones ... MyastheniaGravis #Checklist #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Transplantation including bone ... Etiology: • Pathophysiology ... Reversible course Differential ... the underlying cause ... Syndrome #diagnosis #management
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... Mucous membranes • Bone ... poor nutrition Clinical ... failure to thrive • Ill ... , or any other cause
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... surgery, trauma, and bone-marrow ... can vary from mild ... the underlying pathophysiology ... Syndrome #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... - Pleocytosis: Mild ... Myelitis #diagnosis #management ... #neurology #differential