8 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
common sites: hip, shoulder ... • XR, MRI to ... dx and stage ... #differential #diagnosis ... #causes #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... screening for disease ... normal in mild cases ... levels (VIII, IX ... #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... the diagnosis and ... of liver disease ... liver biopsy or MRI ... #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... NMO-IgG (anti-AQP4) should ... , MOG-IgG test should ... • Infectious causes ... #management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... /CTA • Anterior ... count in the CSF should ... #management #neurology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
involvement: May involve anterior ... Rule out other causes ... - MRI: inflammation ... osteoarticular and skin disease ... #management #Dermatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
proximal muscles of shoulder ... affects the skin, neurologic ... oligoclonal bands • MRI ... tract, and often causes ... drug exposure or Dx
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
the face, or the anterior ... , and back and shoulders ... Muscle atrophy may cause ... had more severe disease ... #dermatology