10 results
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Warfarin and DOAC ... - Dabigatran - ... Rivaroxaban - Apixaban ... #NOAC #comparison ... #rivaroxaban #apixaban
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
#INR #heparin #LMWH ... #NOAC #warfarin ... #coumadin #rivaroxaban ... #Xarelto #apixaban ... #Eliquis #dabigatran
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... dosing and bridging ... Clotmaster #VTE #DOAC ... Anticoagulation #Dabigatran ... #Apixaban #Rivaroxaban
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Reversal Agents - Warfarin ... Kcentra) - Heparin/LMWH ... Protamine sulfate - Dabigatran ... (Praxbind) - Apixaban ... #noac #pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Anticoagulant Agents Warfarin ... Hepatic, 0% Renal Apixaban ... Hepatic, 25% Renal Dabigatran ... Hepatic, 50% Renal Rivaroxaban ... #NOAC #Metabolism
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Weight Heparin (LMWH ... Enoxaparin - Warfarin ... Xa inhibitors - Apixaban ... , rivaroxaban - ... #comparison #table
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
anticoagulant (e.g. warfarin ... accelerates the bridging ... #UFH #DOAC #Dabigatran ... #Apixaban #Rivaroxaban ... #Fondaparinux #NOAC
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Management Cheat Sheet: Warfarin ... , Apixaban, Dabigatran ... , Rivaroxaban ... Anticoagulant #DOAC
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... , edoxaban and rivaroxaban ... direct-acting oral ... anticoagulant; LMWH ... #Cancer #Algorithm
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
For patients on warfarin ... direct acting oral ... of Therapy • Dabigatran ... inhibitor) • Apixaban ... , Edoxaban, Rivaroxaban