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diagnosis causes algorithm cardiology endocarditis weakness anesthesia anesthesiology checklist chronic encephalopathy fatigue hematology hyperthermia infectiousdiseases mds myasthenia myelodysplasia myelodysplastic oncology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Cardio-pulmonary disease • Anemia ... Hyperreflexia • Lead ... • Myasthenia Gravis ... Lambert-Eaton Myasthenic Syndrome ... Peripheral #Weakness #Neurology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Hematologic • Anemia ... Pulmonary Disease Neurologic ... • Myasthenia Gravis ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... dystrophy - Brain stem ... Serologic and EMG ... #diagnosis #management ... #neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... • Toxic/drug: Lead ... Postsynaptic: Myasthenia Gravis ... dystrophies Work ... #Diagnosis #neurology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
• Serotonin syndrome ... Phaeochromocytoma Neurologic ... #Hyperthermia #Differential ... Checklist #Diagnosis #Management ... #Workup
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Diagnosis and Management ... and pernicious anemia ... Pathophysiology ... antibody that works ... #treatment #neurology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... compounds, alcohol, lead ... Workup: • Complete ... blood count with differential ... hematopoietic stem
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
bone marrow or stem ... Etiology: • Pathophysiology ... Reversible course Differential ... #diagnosis #management ... #neurology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Sanguinis, Mitis, Oralis ... Marantic (NTBE) Differential ... ↑ ESR, CRP • EKG ... Leukocytosis, anemia ... Endocarditis #diagnosis #management
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
- Overview and Differential ... Sanguinis, Mitis, Oralis ... Cholesterol emboli syndrome ... ↑ ESR, CRP • EKG ... Leukocytosis, anemia
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