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diagnosis management cardiology endocarditis hematology algorithm anticoagulation cancer differential malignancy oncology apixaban cardiomyopathy checklist coagulation comparison criticalcare dabigatran deficiencies deficiency
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
anticoagulants (DOACs ... filtration rate; DOAC ... anticoagulant; LMWH ... body mass index; VTE ... #DOAC #VTE #Malignancy
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 Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
the mainstay of VTE ... . heparin, LMWH, ... anticoagulant (e.g ... #UFH #DOAC #Dabigatran ... #Fondaparinux #NOAC
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
algorithm for VTE ... risk of recurrent VTE ... ¥LMWH is currently ... DOAC, direct oral ... #DOAC #VTE #Malignancy
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... Medications - Heparin, LMWH ... , warfarin, DOACs ... (e.g. direct factor ... Autoimmune disorders (e.g
Endocarditis checklist Initial evaluation • Peripheral blood cultures (three sets at three different sites) • Additional culture
Echocardiography (TTE ... if suspected (e.g ... consultation • Valve regurgitation ... block (+/- daily EKG ... of infection (e.g
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
aortic and mitral regurgitation ... cultures • 2D Echo TTE ... • TTE nondiagnostic ... ↑ ESR, CRP • EKG ... Marantic: Emboli > Regurgitation
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
cardiomyopathy (e.g ... Avoid Warfarin and DOAC ... hemodynamics (e.g ... LVEF recovery (e.g ... Serial TTE and close
Palpitations - Differential Diagnosis Framework What? • It is an unpleasant awareness or sensation that the heart is
exam • 12-lead ECG ... rhythms: PSVT or VT ... Valvular disease (e.g ... Severe mitral regurgitation ... Severe aortic regurgitation
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
aortic and mitral regurgitation ... cultures • 2D Echo TTE ... ○ TTE nondiagnostic ... ↑ ESR, CRP • EKG ... Marantic: Emboli > Regurgitation
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