10 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... synovitis (40%) Treatment ... AdultOnset #Stills #Disease ... #AOSD #rheumatology ... diagnosis #management #treatment
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
screening for disease ... with established disease ... possible, patients should ... athletic regimens should ... #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell Disease ... predispose to other orthopedic ... common sites: hip, shoulder ... Pain #SickleCell #Disease ... diagnosis #causes #hematology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
criteria, 2 of which should ... Treatment - Mild ... : NSAIDS Treatment ... #AOSD #diagnosis ... #rheumatology #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... of underlying disease ... erythematosus [SLE], AOSD ... Treatment: • Corticosteroids ... #Rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Splenomegaly Treatment ... • Treatment is ... aspirin • Aspirin should ... von Willebrand disease ... #hematology
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
corticosteroids TREATMENT ... Typical MS-like ON: should ... other auto-immune diseases ... Diagnosis #Management #treatment ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... • Bicytopenia Treatment ... • Infection should ... antibiotic therapy should ... #hematology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition Disease ... weird joints (shoulders ... Wrist, MCP or shoulder ... Acute Pseudogout: Treatment ... #Rheumatology #
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
, and back and shoulders ... had more severe disease ... positive patients Treatment ... diagnosis #management #rheumatology