24 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Lumbar Puncture, EEG ... Treatment: ... #SLE #CNS #neurology ... #rheumatology #
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... Hydroxychloroquine *Short ... #SLE #Summary #diagnosis ... #rheumatology #
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... Systemic lupus erythematosus ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... • Malignancy (e.g ... • Malar rash - spares ... #Diagnosis #Rheumatology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... hyperthermia crisis (late sign ... Phaeochromocytoma Neurologic ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Multiple Sclerosis Treatment ... taper 3-7 days - Short ... #management #neurology ... #treatment #MS
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... organ damage • Treatment ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... and Differential Diagnosis ... hypertension and signs ... renal bruit or signs ... Neurologic disorders
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
myasthenia Diagnosis ... Serologic and EMG ... test - Cogan sign ... - Peek sign ... #management #neurology