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diagnosis hematology differential lad lymphadenopathy management diffuse focal hemophagocytic hlh localized lymphohistiocytosis essential et gammopathies glomerulonephritis hemeonc mgus monoclonal multiplemyeloma
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Lymphocytic Leukemia (CBC ... #Causes #Hematology ... #Oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... Artifact (redo CBC ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... differential #diagnosis #algorithm ... #rheumatology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Cr >2 mg/dL or CC ... Causes of false- ... amyloidosis Other causes ... MGUS #diagnosis #hematology ... #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Drugs, Unknown cause ... 100 mg/m2) : in case ... treatment #summary #rheumatology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... Diagnosis: On the CBC ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... Pathophysiology ... of NK cells and CD8 ... Diagnosis #Management #Hematology
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