9 results
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... adenomas that require treatment ... Signs / Symptoms / Complications ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
thickness) - metabolic ... #FeedbackLoop #endocrinology ... #pathophysiology ... #pituitary
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Hypogonad (50%) • Metabolic ... malignancy Pathophysiology ... • Pituitary ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
hypothalamus or pituitary ... Obstructive uropathy, Metabolic ... Treatment is aimed ... at the psychiatric
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Due to neuronal metabolism ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
from hormonal and metabolic ... severe clinical complications ... hyperparathyroidism Treatment ... Differential #Diagnosis #Pathophysiology
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
Anorexia Nervosa: Complications ... Cerebral Atrophy and Metabolic ... mortality rates of all psychiatric ... #pathophysiology ... signs #symptoms #psychiatry
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
Bulimia Nervosa: Complications ... Vomiting may lead to metabolic ... abuse may lead to metabolic ... #pathophysiology ... signs #symptoms #psychiatry
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
hypomagnesemia • Metabolic ... Hypochloremic metabolic ... diarrhea Potential Complications ... Rhabdomyolysis Treatment ... nephrology #management #pathophysiology