72 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
twitter.com/AmyChung #AntiCoagulation ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
PCC (Kcentra) - Heparin ... PCC (Kcentra) #anticoagulation ... #doac #noac #pharmacology ... #hematology #reversal
Heparin Induced Thrombocytopenia (HIT) - Likelihood, Diagnosis and Management
 - HIT Suspected
 - Calculate 4T Score
Heparin Induced ... Diagnosis and Management ... - Start/Stop Heparin ... Algorithm #Diagnosis #Management ... #Hematology
4T Score for Heparin-Induced Thrombocytopenia

Interpretation of the 4T score:
0-3 points:  Low probability (<<1%)
  -
4T Score for Heparin-Induced ... Consider therapeutic anticoagulation ... with non-heparin ... Initiate therapeutic anticoagulation ... Diagnosis #Criteria #Hematology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Anticoagulant #Anticoagulation ... #Loading #DVT #Pharmacology ... #Hematology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
Mechanism of Action in Hepatic ... #Lactulose #pharmacology ... mechanism #ammonia #hepatology ... #pathophysiology
Lower Extremity Venous Thrombosis - Management and Anatomy

Deep - Superficial - Active Bleeding

#LowerExtremity #Veins #Venous #Thrombosis
Venous Thrombosis - Management ... Deep #VTE #DVT #Hematology ... #Management #Anatomy ... #Anticoagulation
Upper Extremity Venous Thrombosis - Management and Anatomy

Deep - Superficial - Catheter Associated

#UpperExtremity #Veins #Venous #Thrombosis
Venous Thrombosis - Management ... Deep #VTE #DVT #Hematology ... #Management #Anatomy ... #Anticoagulation
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
#anticoagulation ... clotting #INR #heparin ... dabigatran #Pradaxa #management ... #pharmacology #
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Anticoagulants #DOACs #anticoagulation ... #Switching #hematology ... #pharmacology