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diagnosis management hematology syndrome cirrhosis metabolism workup activation alkphos apml astalt biliary carcinoma causes cell chemistry cholangitis coagulation dic differentiation
Bilirubin Metabolism - Pathophysiology • Conjugated Bilirubin • Unconjugated Bilirubin By Dr. Khushboo Gala @LouLectures #Bilirubin #Metabolism #Pathophysiology
Bilirubin Metabolism ... - Pathophysiology ... • Conjugated Bilirubin ... #Metabolism #Pathophysiology ... #hepatology #Liver
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... Phosphatase and Bilirubin ... initial insult Bilirubin ... ASTALT #AlkPhos #Bilirubin ... #Hepatology #Pathophysiology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... infection with severe liver ... injury (INR > 2, bilirubin ... mg/dL) or acute liver ... Indications #management #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... cholestasis → Cirrhosis/Liver ... slightly elevated • Bilirubin ... or higher • Liver ... diagnosis #workup #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Renal Failure Treatment ... diagnosis #management #hematology ... #oncology
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline First Line Treatment for HCC with Preserved
First Line Treatment ... with Preserved Liver ... Function Second Line Treatment ... #Management #Hepatology ... Gastroenterology #oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... DIC • Severe Liver ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
thrombocytopenia • Liver ... ↑ AST ↑ ALT ↑ bilirubin ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
: 1) chronic liver ... abnormalities PATHOPHYSIOLOGY ... the left heart TREATMENT ... only definitive treatment ... cirrhosis #diagnosis #hepatology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Occurs in advanced liver ... hepatitis, or acute liver ... Pathophysiology: ... Treatment Overview ... Hepatorenal #Syndrome #Hepatology
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