7241 results
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Causes of Lactate ... The use of lactate ... as a clinical prognostic ... a multitude of clinical ... the appropriate clinical
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
recycles peripheral lactate ... production  increased lactate ... presentation - Clinical
Decompression Sickness - The physical examination revealed diffuse violaceous skin mottling over his trunk and arms
as the elevated lactate ... #Clinical #Derm
Acinetobacter baumanii on culture and microscopy
 - MacConkey agar - Lactose Negative
 - gram negative (often
MacConkey agar - Lactose ... Acinetobacter #baumanii #clinical
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Framework and Clinical ... increased pyruvate and lactate ... Increased pyruvate & lactate ... - Increased Lactate
Food carbohydrates
Starch
Polysaccharides
Salivary amylase
G)
Pancreatic amylase
Lactose
Maltose
Lumen
Lactase
Maltase O
Sucrase
Saccharose Disaccharides
Nat
cotransport
carrier
Villus
epithelial cell
Galactose
Glucose
Glucose
Glucose
Glucose
Fructose
Galactose
Na*- and energy-
dependent
absorption
Glucose
Facilitated
diffusion
#Fructose Monosaccharides
Energy
dependent
Blood capillary
Na+
Pancreatic amylase Lactose ... Maltose Lumen ... Lactase Maltase ... epithelial cell Galactose ... Glucose Fructose Galactose
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
chikungunya, dengue, LaCrosse ... • Common clinical ... CSF Lactate: Good ... meningitis • CSF-lactate
Leigh Syndrome 
History: 19-month-old girl with hypotonia, developmental 
delay, failure to thrive, and bilateral optic disc
disease • +/- lactate ... Leigh #Syndrome #Clinical
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days)
Exclude:
1. Causes of acute diarrhea
2. Lactose intolerance
3.
Lactose intolerance ... Normal fecal fat: Lactose ... intolerance, Sorbitol, lactulose
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Pathogenesis and clinical ... Creatinine kinase (CK), lactate