10 results
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... acute myeloid leukemia ... neutrophils #AML #Clinical ... #Hematology #Pathology ... #Smear
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... features in most cases ... #APL #APML #Pathology ... #Hematology #Clinical ... #Smear
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
Prolymphocytes In our case ... T-prolymphocytic leukemia ... Prolymphocytes #Smear ... #Peripheral #Pathology ... #Microscopy #Clinical
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... -> AML: Blast crises ... develop leukostasis syndrome ... • Peripheral smear ... • Tumor lysis syndrome
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... • Richter’s Syndrome ... • Sezary syndrome ... #diagnosis #workup
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Peripheral Smear ... • Hairy Cell Leukemia ... Workup: • Complete ... Peripheral blood smear
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Peripheral Blood Smear ... Syndrome: 3d of ... The table below ... BloodSmear #microscopy #pathology ... #clinical
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... and petechiae Causes ... virus (EBV) • Leukemia ... Anemia #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... organ damage Clinical ... • Peripheral smear ... Schistocytes, helmet cells ... Treat primary cause