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diagnosis differential management anemia blood erythematosus hemophagocytic hlh lupus lymphohistiocytosis normocytic polycythemia product reactions systemic transfusions treatment vasculitis workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management Summary ... Manifestations: Malar rash ... Positive in 60-80% of cases ... Diagnosis #Management #Summary ... #rheumatology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... RA, SLE, PRV, Chronic ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... management #treatment #summary ... #rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... Too many cells in ... Better call hematology ... some time, let’s see ... #workup #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusions One Pager Summary ... maculopapular rash ... Causes purpura & ... potassium from lysed cells ... diagnosis #management #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Multinucleated giant cells ... , mucositis • Rash ... tract, and often causes ... Differential #Diagnosis #Rheumatology
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