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diagnosis differential clinical algorithm management oncology smear thrombocytosis secondary skin bloodsmear chronic cll generalized lymphocytic mds microscopy myelodysplastic path platelets
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Microangiopathic hemolytic ... Microspherocytes: Autoimmune hemolytic ... #Peripheral #Blood ... Smear #Analysis #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
AIHA • Anemia ... type ± C3d • Blood ... 2) LOOK FOR a cause ... #management #treatment ... #rheumatology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... Diagnosis #Algorithm #Causes ... #Hematology
Ecchymosis: Bluish discoloration of skin caused by bruising with resultant subcutaneous collection of blood. Charlie Goldberg, M.D. -
discoloration of skin caused ... collection of blood ... Images #Clinical #Dermatology ... Ecchymosis #Arm #Photo ... #UCSDH
Leukemic skin Infiltrate: Patient with known Acute Myelogenous Leukemia presented with diffuse bullous lesions (not shown). These
cells. ... Goldberg, M.D. - UCSD ... Images #Clinical #Photo ... #Dermatology #SkinRash ... #AML #UCSDH
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Chronic Myelogenous Leukemia ... effect following treatment ... Iron deficiency anemia ... #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... spherocytosis, Hemolytic ... • Target cells ... Schistocytes - Hemolytic ... #differential #hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Reactive: • Anemia ... /blood loss (Fe ... Chronic Myeloid Leukemia ... Differential #Diagnosis #causes ... #Platelets #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic ... anemia. ... polychromatophilic cells ... #anemia #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... iron deficiency, hemolysis ... Chronic myeloid leukemia ... #hematology #secondary
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