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hematology management myelodysplastic treatment anemia aplastic cerebritis cns differential disruptors erythematosus fracture healing henochscholeinpurpura hsp hypoxemia hypoxia iga leukemia lupus
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
(MD) - Diagnosis ... = funny-shaped cells ... old, ~10,000 new cases ... #MDS #Diagnosis ... treatment #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Out Secondary Causes ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... (MDS) (normal or ... result from low blood ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
oxygen in the blood ... CYTOPATHIC HYPOXIA - Cells ... Nick Mark MD @nickmmark ... #differential #diagnosis ... #causes #pathophysiology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology ... #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Maheswaranathan, MD
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
endothelial lining of blood ... various inflammatory cells ... nephrotic/nephritic syndrome ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
disrupts local blood ... osteoprogenitor cells ... Fluoroquinolones - Causes ... #msk #Staging #pathophysiology ... #diagnosis #disruptors
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