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diagnosis differential oncology product transfusion algorithm anemia aplastic basophilia basophils classification clinical coagulation comparison dic disorders disseminated eosinophil eosinophilia gangrenosum
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
the total white blood ... similarly to mast cells ... during an allergic reaction ... Or Inflammatory Reactions ... #hematology #basophils
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... for secondary causes ... eosinophilia (common causes ... allergy, drug reaction ... Differential #diagnosis #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... potassium from lysed cells ... Transfusion #diagnosis #management ... #hematology #reactions
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... of high parity blood ... without other cause ... , and CXR with pulmonary ... #hematology #diagnosis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... potassium from lysed cells ... Transfusions #diagnosis #management ... #hematology #reactions
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Workup: • Full Blood ... marrow biopsy - if blood ... classification #hematology ... #oncology #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... Schistocytes, helmet cells ... Treat primary cause ... #treatment #management ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... number of CD34+ cells ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
disease, drug reactions ... pulses, bruits, or blood ... Multinucleated giant cells ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Pyoderma Gangrenosum (PG) 50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
neutrophils & T-cells ... Management of PG ... medications in most cases ... #PG #clinical #photo ... #dermatology #ulcer
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