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diagnosis hematology oncology management algorithm anemia hemolytic agglutinin aids causes chronic classification cll cns cold disease eosinophil eosinophilia gap globulin
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
smear: Smudge cells ... or basket cells ... lymphoproliferative disorders ... Agranulocytosis 3. ... Leukemia #diagnosis #workup
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... #Algorithm #Differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Algorithm • Sickle cells ... Consider sickle cell ... Consider RBC membrane disorder ... Diagnosis #Algorithm #workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Disease 3 ... Antibodies[PCH] 3. ... younger pts) Differential ... sensitize red blood cells ... hemolytic #anemia #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Neutropenia • Platelet Disorders ... Workup: • Complete ... blood count with differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... Reed-Sternberg cells ... • Autoimmune disorders ... symptoms in 1/3 ... Hodgkin Lymphoma Workup
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
in HIV / AIDS - Differential ... less than 200 cells ... more than 200 cells ... Suspect in movement disorders ... - Generally >3
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Hyperuricemia • Hyponatremia ... obstruction 3. ... kidney tubular cells ... output: 200 ml/hr 3.
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
level of myelitis 3. ... - More than 2/3 ... Pleocytosis > 100 cells ... diagnosis #management #neurology ... #differential
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
arises from plasma cells ... from the plasma cells ... Biopsy: Solitary disorder ... monoclonal plasma cells ... clonal plasma cells
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