7 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... leukapheresis - TLS ... Lysis of tumor cells ... #diagnosis #management ... #hematology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of UMN and LMN signs ... fasciculations Common Symptoms ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Diagnosis and Management ... caucasian • Symptoms ... Unilateral • Signs ... Neuritis #Diagnosis #Management ... #treatment #rheumatology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
anti-coagulation • Hematologic ... Retina • Ganglion cells ... after CRAO -> Pale Optic ... ophthalmology #diagnosis #signs ... #symptoms
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... systemic sx + signs ... GCA #Temporal #Signs ... #Symptoms #Diagnosis ... #Management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... < 30 years • Aorta ... Arteritis): • Aorta ... • Progressive symptoms
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... Pleocytosis > 100 cells ... for brain and/or optic ... Myelitis #diagnosis #management